Name: Vernice Peterson

Affiliation: Department of Physiology, School of Biomedical Sciences, Faculty of Health Sciences,
University of the Witwatersrand, Johannesburg, South Africa.

Email: vernice.peterson@wits.ac.za

Linkedin: www.linkedin.com/in/vernice-peterson-b47130bb

ORCID:  https://orcid.org/0000-0001-7602-3549

Tell us about yourself.

I am a senior academic with a PhD in cardiovascular physiology. I currently work in the Department of Physiology at Wits University in Johannesburg, South Africa, and have more than 10 years of research experience in basic and clinical science. In addition, I am the co-founder of a satellite cardiovascular laboratory linked to the Wits Cardiovascular Pathophysiology and Genomics Research Unit (CPGRU).

What are your research interests?

My core research focuses on cardiac function and haemodynamic mechanisms associated with cardiovascular diseases such as hypertension, coronary artery disease and heart failure. I have a strong interest in using integrated approaches, such as echocardiography and central pressure measurements, to identify novel mechanisms of cardiovascular disease in underrepresented communities. Using these tools in translational research, I aim to ultimately improve health outcomes and reduce cardiovascular disparities in resource-limited settings. In addition, I have a passion for cardiovascular epidemiology and implementation sciences.

What are you working on right now?

I am currently working on several intriguing research projects in cardiovascular health. Some of these projects explore factors contributing to vascular aging; I am investigating cardiovascular disease in tuberculosis and HIV, evaluating the affordability of cardiovascular therapies and examining global differences in hypertension manifestations. Although these are just a few examples, each project I am working on aims to advance knowledge in cardiovascular research while addressing cardiovascular health disparities, the importance of utilising innovative technologies and promoting research training of future scientists.

What do you hope to achieve in the field of hypertension over the next 5 years?

As a physiologist, my foundation lies in understanding mechanisms, and based on this, I aim to contribute further to improving the understanding of hypertension and the importance of tailored interventions. Through my commitment to conducting translational research using multi-faceted approaches, I strive to foster and promote more in-country and global partnerships that will inform hypertension research, management and policy. All of which speaks to broader communities, vulnerable populations and researchers. In addition, I aim to foster and train the next generation of cardiovascular scientists and equip them with the necessary tools and knowledge to address the evolving challenges faced in understanding hypertension.

What challenges have you faced in your career to date?.

Throughout my career, I have encountered several challenges, particularly with research funding constraints and the ongoing endeavour to bridge the gap between basic science and real-world applications. As a woman in science, one of my most significant challenges has been balancing child and family care while advancing my professional growth. The latter is an ongoing journey for me, and I am incredibly grateful for the solid support system I have in place. As a result, I can ensure that my ‘number-1-supporters’ are well cared for, especially during my work-related travels.

Which of your publications are you proudest of and why?

I am proud of all my papers! But if I had to choose, it would be “Metformin Prevents Low- dose Isoproterenol-induced Cardiac Dilatation and Systolic Dysfunction in Male Sprague Dawley Rats”, published in the Journal of Cardiovascular Pharmacology (doi: 10.1097/FJC.0000000000001172). I prepared this paper while I was on maternity leave. While working for a ‘new little’ boss, I thoroughly enjoyed the mechanistic approach of this work. The combination of metabolic mechanisms, chronic sympathetic stimulation of the heart, repurposing metformin, and integrating technical approaches captivated the physiologist in me. In addition, this paper highlights the importance of conducting research from ‘bench-to-bedside’.

What is your favourite manuscript from a lab other than your own?

One of my favourite papers outside my lab was a technical review, “Large Artery Stiffness Assessment Using SphygmoCor Technology,” by Mark Butlin and Ahmad Qasem, published in Pulse (doi: 10.1159/000452448). I love technical papers and work that speaks to practical applications that can be easily implemented. The review paper articulates most of my work on haemodynamic mechanisms and the cardiovascular system. The authors eloquently compiled evidence from numerous prolific research studies that contributed significantly to a global understanding of non-invasive pulse wave velocity and central blood pressure measurement.

What are your passions outside of work?

I cherish spending time with my family. We always make time to explore new places, play new games or build Lego. I love being creative and doing hands-on projects. When I get a chance, I love to bake! I enjoy the science behind creating a variety of sweet delicacies, from cupcakes to wedding cakes, and the best part…is sharing them with others. Travelling enriches my life, allowing me to collect art and learn about diverse cultures. Each journey brings a sense of wonder, connecting me with new people and experiences that significantly enhance my family life and professional perspective.