International Society of Hypertension

New Investigators Network

Our Fellows Work


Morphologic and Functional Heart Abnormalities Associated to High Modified Tei Index in Hypertensive Patients.

Tissera G, Piskorz D, Citta L, Citta N, Citta P, Keller L, Bongarzoni L, Mata L, TommasiA. High Blood Press Cardiovasc Prev, 2016 Dec;23(4):373-380. PMID: 27623974

Gabriel Tissera (Argentina)

1)      Summarize your work in one sentence.

The aim of the study was to determine the type and frequency of morphologic and functional heart abnormalities associated to abnormal modified Tei Index in untreated hypertensive (HBP) patients (p) with preserved ejection fraction.

2) Summarize your findings in one sentence.

The study concluded that subclinical left ventricular dysfunction is frequent in untreated HBP, even in the absence of left ventricular hypertrophy and that modified tissue Doppler Tei index is a useful tool for the diagnosis of this subclinical left ventricular dysfunction.

3) Which were the more important methods you used in this work? If it is not a traditional method you can briefly explain the concept of that methodology.

We performed a case–control study. Three groups were compared: (1) HBP without left ventricular hypertrophy (LVH); (2) HBP with LVH; (3) non-HBP controls. Ejection fraction > 54 % identified pEF. LVH was measured by Devereux method. For the statistical analysis ANOVA test adjusted by sex and age was used, p>0.05 was considered statistically significant. A tissue Doppler original Tei method adaptation was used for the evaluation of systolic and diastolic function.   This technique is easier than the Tei proposal since data can be obtained on line in just one window and one beat.

4) What did you learn from this paper, what was your take-home message

Untreated hypertensive patients with an ejection fraction higher than 54 %, with or without LVH, have incipient and subtle abnormalities in left ventricular function which could be easily detected by tissue Doppler obtained Tei index.


Latest Tweets:

The ISH is positively committed to opposing discrimination against people on the grounds of gender, race, colour, nationality, religion, marital status, sexual orientation, class, age, disability, having dependants, HIV status or perceived lifestyle.