Association Between High and Very High Albuminuria and Nighttime Blood Pressure: Influence of Diabetes and Chronic Kidney Disease.
Ruiz-Hurtado G, Ruilope LM, de la Sierra A, Sarafidis P, de la Cruz JJ, Gorostidi M, Segura J, Vinyoles E, Banegas JR. Diabetes Care, 2016 Oct; 39(10):1729-37. PMID:27515965
Gema Ruiz-Hurtado (Spain)
Gema Ruiz-Hurtado is the leader of the Translational Laboratory of Cardiovascular Research at the Institute of Research i+12 in the Hospital Universitario 12 de Octubre, Madrid, Spain. Her experimental and clinical research activities have focused on the study of new molecular targets and biomarkers involved in hypertension and cardiovascular and renal disease.
1) Summarize your work in one sentence:
This study examined whether one of the most dangerous forms of hypertension, the nocturnal hypertension, might be influenced by the presence of diabetes or chronic kidney disease.
2) Summarize your findings in one sentence.
Systolic blood pressure during the night (nighttime BP) is strongly elevated, increasing 14.5 mmHg higher with the presence of severe albuminuria in patients with chronic kidney disease and diabetes
3) Which were the more important methods you used in this work? If it is not a traditional method you can briefly explain the concept of that methodology.
To use the Spanish Ambulatory Blood Pressure Monitoring Registry (directed by Dr. Luis Miguel Ruilope) which is composed of a large nationwide population sample. In this study 16.546 patients were recruited across all geographical communities covered by the national health care system in Spain.
4) What did you learn from this paper, what was your take-home message?
“Do not let that your kidney and diabetes break your heart: night-time blood pressure as a relevant warning alarm”