Association of age-dependent height and bone mineral density decline with increased arterial stiffness and rate of fractures in hypertensive individuals.
El-Bikai R, Tahir MR, Tremblay J, Joffres M, Šeda O, Šedová L, Awadalla P, Laberge C, Knoppers BM, Dumas P, Gaudet D, Ste-Marie LG, Hamet P. J Hypertens. 2015 Apr;33(4):727-35. PMID: 25915877
Rana El Bikai (Lebanon)
1) Summarize your work in one sentence.
Our work focuses on the association of osteoporosis with high blood pressure and arterial stiffness. The study was carried in a cross-sectional population based cohort (CARTAGENE) and validated in 2 other cohorts (The Canadian Heart Health Study and a family cohort the Saguenay Lac Saint-Jean, a region of Quebec).
2) Summarize your findings in one sentence.
Our analysis showed that arterial stiffness, low bone mineral density and fractures are significantly associated with high blood pressure.
3) Which were the more important methods you used in this work? If it is not a traditional method you can briefly explain the concept of that methodology.
At the recruitment stage different methods were used, one of which is the bone mineral density measurement (BMD). Usually the BMD is measured at the hip level using an X-ray based machine (DEXA). In the context of this study, BMD was measured on the heel, using the Achilles Quantitative Ultrasound System. With this method the speed of sound and the frequency-dependent broadband ultrasound attenuation (BUA) are combined to form a clinical measures such as the t-score (traditionally used by physicians).
4) What did you learn from this paper, what was your take-home message?
In this paper we show that low bone mineral density is significantly associated with high blood pressure and arterial stiffness.
There is a potential relevance of evaluating bone health in hypertensive men.