International Society of Hypertension

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What's On My Desk


James Sharman, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

Posted on 11/07/2018

Our latest “What’s on my desk” comes from Prof. James Sharman, Menzies Institute for Medical Research, Hobart, Tasmania, Australia (winner of the ISH 2018) Distinguished Mentor Award).

James SharmanManuscript:

Atrial Fibrillation Detection During 24-Hour Ambulatory Blood Pressure Monitoring Comparison With 24-Hour Electrocardiography

Anastasios Kollias, Antonios Destounis, Petros Kalogeropoulos, Konstantinos G. Kyriakoulis, Angeliki Ntineri, George S. Stergiou

© 2018 American Heart Association, Inc.

Hypertension is available at DOI: 10.1161/HYPERTENSIONAHA.117.10797



 Why I selected this manuscript?

Atrial fibrillation (AF) is a common arrhythmia of older people that increases risk for stroke, but the condition can often go unrecognized, and there is a need for better community screening methods. Conventional automated blood pressure devices generally have trouble measuring blood pressure accurately when an individual has an irregular heart beat such as AF. However, special blood pressure devices have been developed to try and recognise AF. This nicely conducted study by Dr Kollias and colleagues tested the ability of a novel 24 hour blood pressure device to detect AF in elderly people by simultaneous comparison with the reference standard of continuous ECG monitoring. The blood pressure device performed exceptionally well in detecting AF, albeit with some false-positives that suggest some further refining may be needed. In any case, the findings support the hypothesis put forward by the investigators, that routine blood pressure monitoring offers an additional opportunity to screen for AF in older people.

The work piqued my interest because it is well conducted and has strong potential for clinical translation.

Professor Sharman is a clinical physiologist with special interest in accurate blood pressure measurement, ventricular-vascular interaction and exercise haemodynamics. He is a Senior Research Fellow and Deputy Director at the Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia. He also heads the Blood Pressure Research Group and has undertaken some of the first studies to understand the physiology and clinical relevance of aortic blood pressure.



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