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Visit-to-visit (long-term) and ambulatory (short-term) blood pressure variability to predict mortality in an elderly hypertensive population

Chowdhury EK, Wing LMH, Jennings GLR, Beilin LJ, Reid CM, ANBP2 Management Committee.

Journal of Hypertension, 2018 36(5):1059–1067

doi: 10.1097/HJH.0000000000001652

Enayet K. Chowdhury (Australia)

1) Summarize your work in one sentence.

Blood pressure (BP) variability is an important predictor of future cardiovascular events among hypertensive people, though it is still unclear which type of BP variability measure (estimated from either short-term ambulatory reading-to-reading or long-term clinic visit-to-visit BP records) has the best prognostic capacity.

2) Summarize your findings in one sentence.

In this post-hoc analysis we found that short-term BP variability (i.e. day-time, weighted day–night) has better prognostic accuracy for mortality than long-term BP variability.

3) Which were the more important methods you used in this work? If it is not a traditional method you can briefly explain the concept of that methodology.

In this study we compared short-term (ambulatory) and long-term (visit-to-visit) BP variability within the

same population with mortality outcome over a median 11 years follow-up. 

4) What did you learn from this paper, what was your take-home message?

Short-term ‘daytime’ and ‘weighted day–night’ systolic BP variability measured from the ambulatory BP recordings was a better predictor of mortality in elderly treated hypertensive patients compared to the long-term BP variability measured from the clinic visit-to-visit BP recordings. This information on BP variability estimated from an ambulatory BP recording is likely to assist clinicians to identify individuals with increased cardiovascular risk.


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